In this previously recorded episode of The Health Edge John and Mark examine autoimmunity and non-pharmacologic strategies for bringing greater balance and “tolerance” to one’s immune response. They offer some lifestyle considerations for reducing the magnitude of one’s immune response on itself.
In this episode of The Health Edge Mark and John discuss important cardiovascular risk biomarkers for measurement and tracking.
In this episode of The Health Edge Mark and John discuss common single nucleotide polymorphisms (SNPs) commonly found on consumer-based gene analyses like 23 and Me. They discuss the implications for lifestyle, nutritional, and thoughtful supplementation interventions.
In this episode of The Health Edge Mark and John discuss the research linking lifestyle with breast cancer risk and prognosis.
References Breast Cancer Risk-Survival Diabetes
References – Mindfulness Breast Cancer
References – Inflammation and Breast Cancer
Insulin resistance and breast ca
Obesity and cancer mechanisms Nature Reviews Endocrin 2014 p455-
In this episode of The Health Edge Mark and John discuss the current research linking the microbiome to human health. They review why we have fewer and less diverse “Fellow Travelers” and how we can begin to think about restoring this critical ecosystem legacy.
Cell Host Microbe 2017 p84-Dysbiosis and disease
Microbiome and neurotransmitters
Masters of Host Development and Physiology
Sonnenburg-Fiber and Microbiota health Cell
Personalized Nutrition Glycemic Response Cell 2015
In this episode of The Health Edge Mark and John discuss the metabolic disruptors that increase the risk of Alzheimer’s and other “brain-related diseases”. The explore lifestyle interventions proven to restore many of these risk factors. Might Alzheimer’s be preventable or reversible? The research is suggesting a very surprising answer!
B-OH Butyrate and NLRP3 Inflammasome
Health Benefits of Nutritional Ketosis
Nutritional Mental Health 2015
PowerPoint on Core Imbalances Influencing Mind and Mood
In this episode of The Health Edge Mark and John discuss the connection between mitochondrial function and the risk-progression of many chronic complex diseases. They explore the many “environmental” drivers and offer some lifestyle interventions to improve mitochondrial reserve-resilience.
Mitochondrial Cocktail Podcast
In this episode of The Health Edge Mark and John discuss protein intake, sources, and health. They touch on:
Both Low and High Serum IGF-I Levels Associate with Cancer Mortality in Older Men
Circulating Insulin-Like Growth Factor I Mediates Effects of Exercise on the Brain
Human conditions of insulin-like growth factor-I (IGF-I) deficiencyIGF-1 promotes the development and cytotoxic activity of human NK cellsInsulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk- pooled individual data analysis of 17
prospective studiesDemonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive declineInsulin-like growth factor-(IGF)-axis, inflammation, and glucose intolerance among older adults
In this episode of The health Edge Mark and John discuss the critical role magnesium plays in human health and resilience. They discuss testing, best food sources for magnesium and supplement consideration.
In this episode of The Health Edge Mark and John discuss the inherent limitations of looking at exercise simply as a “caloric burn” endeavor.
