In this episode of The Health Edge Mark and John review a recent study published by the Journal of the American College of Cardiology, Trends and Disparities in Cardiometabolic Health Among U.S. Adults, 1999-2018. Mark and John reflect on how we got here and why this is so important to recognize and respond to. Lifestyle drivers and interventions are discussed that have the potential to powerfully reverse these concerning trends. Article referenced: https://pubmed.ncbi.nlm.nih.gov/35798…

You Tube recording can be found at: https://www.youtube.com/watch?v=_lBUR_llqfA&t=9s&ab_channel=TheHealthEdge

Is it possible that consuming too much fruit could be detrimental to your health? Are all fruits the same? In this recording of The Health Edge Mark and John will explore the relationship between dietary fructose intake (from sugar and high fructose corn syrup and fruits), endogenous metabolic conversion of glucose to fructose (high glycemic foods), and high salt intake (> 5,000 mg sodium/day) with high uric acid cardiometabolic syndrome risk. The evolutionary biologic importance of these pathways as an ancient survival mechanism when food sources were limited has become a major driver of chronic, complex disease in a contemporary context of high sugar and abundant year-round fruit availability. They elaborate on the research of Robert Lustig MD (UCSF), Richard Johnson MD (University of Colorado)and Robert Ludwig MD, PhD (Harvard). Enjoy!

In this episode of The Health Edge Mark and John review two papers that suggest higher levels of vitamin D via supplementation may slow our biologic clocks as measured by epigenetic methylation patterns. The implications are fascinating! YouTube link: https://youtu.be/O3UD62Pk9fE Papers reviewed: Vitamin D supplementation is associated with slower epigenetic aging https://pubmed.ncbi.nlm.nih.gov/35562… Effects of Vitamin D3 Supplementation on Epigenetic Aging in Overweight and Obese African Americans With Suboptimal Vitamin D Status: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/30256…

In this episode of The Health Edge Mark and John review a recently published paper affirming proof of concept: healthy lifestyle may in fact reverse biologic aging or slow “biologic clocks” via epigenetic methylation patterns. 

Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064200/

You Tube video can be seen here:

https://www.youtube.com/watch?v=MQahbN4pzxI&t=2s&ab_channel=TheHealthEdge

June 2022

In this episode of The Health Edge, Mark shares a recording from January 21, 2022 reviewing the current science of aging and longevity. This was the first of a series of 6 webinars sponsored by OLLI Berkshires. https://berkshireolli.org/ScienceOfAgingWinter22

In this episode of The Health Edge Mark and John review a paper demonstrating significant reductions in NAFLD with both 5:2 fasting mimicking or LCHF over just 12 weeks. Article can be found at: https://www.jhep-reports.eu/article/S2589-5559(21)00032-X/fulltext

In this episode of The Health Edge mark and John review an important paper that suggests obesity to be more a consequence of higher insulin than a cause. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2749271

In this Health Edge videocast, John and Mark review a recent paper published in the New England Journal of Medicine that links higher intake of high-glycemic foods and beverages with higher all-cause mortality and cardiovascular disease. https://www.nejm.org/doi/full/10.1056/NEJMoa2007123

This is a recent interview with Drew Pearlman, a marvelous holistic health documentary filmmaker.

Dr. Mark Pettus is a triple-board certified Internist, Nephrologist, and Integrative Medicine physician practicing for over 25 years. He is also the author of two books, The Savvy Patient: The Ultimate Advocate for Quality Health Care and It’s All in Your Head: Change Your Mind, Change Your Health. He hosts The Health Edge Podcast along side John Bagnulo. Mark tells us that when it comes to the pandemic, there is a real threat out there, but there is a lot you can do with food + lifestyle to empower your health and the health of your loved ones. During these challenging times, Mark says that we must come together as a community and care for one another. He says that life is a journey meant to be shared. This episode is filled with deep wisdom and lots of heart.