The Health Edge: Is Alzheimer’s Preventable and Reversible?

In this episode of The Health Edge Mark and John discuss the metabolic disruptors that increase the risk of Alzheimer’s and other “brain-related diseases”. The explore lifestyle interventions proven to restore many of these risk factors. Might Alzheimer’s be preventable or reversible? The research is suggesting a very surprising answer!

B-OH Butyrate and NLRP3 Inflammasome

Health Benefits of Nutritional Ketosis

Nutritional Mental Health 2015

PowerPoint on Core Imbalances Influencing Mind and Mood

MMF metabolic Tune Up

Neuropeptides and microbiota

Bredesen-reversing Alzheimers

The Health Edge: Mitochondrial Resuscitation

In this episode of The Health Edge Mark and John discuss the connection between mitochondrial function and the risk-progression of many chronic complex diseases. They explore the many “environmental” drivers and offer some lifestyle interventions to improve mitochondrial reserve-resilience.

Mitochondrial Cocktail Podcast

The Health Edge: Protein, IGF-1 and Health

In this episode of The Health Edge Mark and John discuss protein intake, sources, and health. They touch on:

  • How much protein is sufficient for most
  • What are the differences between plant and animal protein sources
  • What are the benefits and risks of IGF-1 from a health perspective

Insulin, IGF-1 and Cancer

Red Meat CVD Meta 2010

Meat consumption and mortality – results from the European Prospective Investigation into Cancer and Nutrition

Both Low and High Serum IGF-I Levels Associate with Cancer Mortality in Older Men

Insulin-Like Growth Factor I, IGF-Binding Protein 3, and Lung Cancer Risk in a Prospective Study of Men in China

Meta-Analysis and Dose-Response Metaregression- Circulating Insulin-Like Growth Factor I (IGF-I) and Mortality

Circulating Insulin-Like Growth Factor I Mediates Effects of Exercise on the Brain

Human conditions of insulin-like growth factor-I (IGF-I) deficiencyIGF-1 promotes the development and cytotoxic activity of human NK cellsInsulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk- pooled individual data analysis of 17

prospective studiesDemonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive declineInsulin-like growth factor-(IGF)-axis, inflammation, and glucose intolerance among older adults